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Rosemary Mazanet, MD, PhD 

Clinician Scientist with Extensive Expertise in Clinical Development 

Career Highlights

  • She has been an independent director on numerous boards, including most recently MasTherCell, Inc and is a Trustee at the University of Pennsylvania Health System

  • Co-Founder of Apelles Investment Management, LP and serves as Partner and Chief Scientific Officer

  • President of Rosemary Mazanet LLC

  • A clinician scientist with decades of experience in clinical development and healthcare investing   

  • After training at the Brigham and Women’s Hospital and the Dana-Farber Cancer Institute where she was on clinical faculty, she joined Amgen in 1993 to lead oncology clinical research. The teams she led filed successful INDs, sBLAs, and BLAs, and she presented those programs at FDA BRMAC/ODAC meetings

  • Dr. Mazanet joined Oracle Partners LLC in New York as a General Partner and has been a presence in public equity and private equity biotech and specialty pharma since that time

  • In addition to serving as a life sciences management and investment professional, she has served as an executive at several companies and led development programs ranging from IND submission through NDA approval and commercial launch

  • Involved in the restructuring of biotech development programs, as well as strategic development of drugs licensed directly from academic institutions


  • MD and PhD: University of Pennsylvania

  • BA, Biology: University of Virginia

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